Medicine

Adults with Autoimmune Rheumatic Diseases Should Get Updated COVID-19 Vaccines

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VaccinationCOVID-19Autoimmune diseases

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A large-scale analysis of 60,980 U.S. adults with autoimmune rheumatic conditions who contracted COVID-19 between December 2020 and August 2024 found that those who received booster or updated COVID-19 vaccines had lower hospitalization rates compared to individuals who only completed the initial vaccine series or remained unvaccinated. The study, published in Arthritis & Rheumatology, specifically examined outcomes in patients with conditions like rheumatoid arthritis and lupus, populations often excluded or underrepresented in initial vaccine trials.


This research provides critical evidence that updated COVID-19 vaccines offer meaningful protection for immunocompromised patients with autoimmune conditions, a group at higher risk for severe COVID-19 outcomes. The findings support clinical recommendations for this vulnerable population to receive booster doses and stay current with updated vaccine formulations.


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In an Arthritis & Rheumatology analysis of data on 60,980 U.S. adults with autoimmune rheumatic conditions who developed COVID-19 between December 2020 and August 2024, those who received booster or updated (2023–2024) COVID-19 vaccines were less likely to be hospitalized for COVID-19 than those who received only the initial vaccine series or were unvaccinated.

Source: Should adults with autoimmune rheumatic conditions receive updated COVID-19 vaccines?