Physics

Advanced Biosensor Could Revolutionize Disease Detection Using Terahertz Light

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This numerical study presents a terahertz metasurface biosensor design with high quality factor (Q-factor) operating across multiple frequency bands for detecting changes in refractive index in biological samples. The metasurface architecture demonstrates enhanced sensitivity through sharp resonance peaks that shift in response to minute variations in the refractive index of the surrounding medium. The multiband capability allows simultaneous detection at different frequencies, potentially improving measurement accuracy and reliability in biomedical applications.


High Q-factor terahertz biosensors could enable rapid, label-free detection of biomolecules, disease markers, and cellular changes with improved sensitivity compared to existing methods. The multiband operation may facilitate more comprehensive analysis of biological samples in medical diagnostics, drug development, and biosecurity applications.


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Source: High Q-factor multiband terahertz metasurface biosensor for biomedical refractive index sensing: a numerical study