Chemistry

Ancient molecules helped each other form in early Earth’s chemical soup

How the science connects

CatalysisAbiogenesisRNA world hypothesis

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Researchers have demonstrated that peptides and RNA can form simultaneously under prebiotic conditions through a process called cross-catalytic enhancement, where each type of molecule helps catalyze the formation of the other. This finding challenges the long-standing debate about whether proteins or nucleic acids came first in the origin of life, suggesting instead that both could have emerged together in early Earth conditions. The experimental work shows that amino acids and nucleotides can co-polymerize when present in the same environment, with each polymer type accelerating the synthesis of the other.


This research provides a potential solution to the chicken-and-egg problem in origins of life research, offering a plausible pathway for how the fundamental building blocks of life could have arisen simultaneously rather than sequentially. The findings could reshape our understanding of how life emerged on Earth and inform the search for life on other planets.


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Source: Simultaneous formation of peptides and RNA via prebiotic cross-catalytic enhancement