AI Insight
This study investigated whether the triglyceride glucose-body mass index (TyG-BMI) predicts the risk of requiring repeat percutaneous coronary intervention (PCI) in patients who previously underwent the procedure. Using data from 2015-2025 from a community health center, researchers found no significant association between TyG-BMI levels and repeat PCI risk, even when patients were grouped by their glucose metabolism status (normal, prediabetic, or diabetic).
Why it matters
The findings suggest that TyG-BMI, despite being linked to coronary heart disease development, may not be useful for predicting which PCI patients will need repeat procedures. This challenges the utility of this index as a risk stratification tool in post-PCI patient management and suggests clinicians should rely on other markers for follow-up planning.
by Weiqiang Fei, Feng Yang, Yongbang Zhu, YiNa Le, Shan Wang, Danxia Sun, XiaoXu Zhang
Most patients undergoing percutaneous coronary intervention (PCI) are diagnosed with coronary heart disease (CHD). The triglyceride glucose‑body mass index (TyG‑BMI) has been reported to be associated with CHD. This study aimed to investigate the association between TyG‑BMI and the risk of repeat PCI among post‑PCI patients, with additional exploratory stratification analyses according to glucose‑metabolism status. Data for this study were derived from resident health‑record follow‑up records of Yipeng Community Health Service Center, covering January 2015 to January 2025. Logistic regression models and restricted cubic spline (RCS) were used to evaluate the association between TyG‑BMI and the risk of repeat PCI among post‑PCI patients, with exploratory stratification by glucose‑metabolism status. Logistic regression and restricted cubic spline analyses showed no significant linear or nonlinear association between TyG‑BMI and repeat PCI (OR=0.999,95%CI:0.994 ~ 1.003, P = 0.534; nonlinear χ2 = 0.91, df = 3, P = 0.8223). Stratified analyses by glucose metabolism status also revealed no significant correlation in any stratum(P > 0.05). No independent association between TyG‑BMI and repeat PCI was identified in post‑PCI patients, even within different glucose‑metabolism strata. Relevant findings require further verification in larger prospective cohorts.