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Blood tests reveal why astronauts get constipated in space

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Gut microbiomeSpace medicineMicrobial metabolism

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Research indicates that spaceflight causes significant changes to the gut microbiome within weeks, leading intestinal bacteria to metabolize more protein as digestive transit time slows. This microbial shift appears to be a key factor behind the constipation commonly experienced by astronauts during space missions. The findings are based on blood test analysis that reveals these gut-related metabolic changes.


Understanding and potentially mitigating these digestive changes is critical for astronaut health and mission success, particularly for long-duration missions such as planned trips to Mars. The research could also provide insights into gut health issues on Earth related to reduced mobility or altered digestive transit times.


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Spaceflight may dramatically change the gut within weeks, causing bacteria to break down more protein as food moves more slowly through the intestines. The shift could help explain astronaut constipation and may have wider effects on health, making it an important concern for future missions to Mars.

Source: Blood tests reveal why astronauts get constipated in space