Medicine

Case 31-2026: A 42-Year-Old Pregnant Woman with Vaginal Hemorrhage

How the science connects

Prenatal diagnosisHemorrhageObstetrics

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This case report from the New England Journal of Medicine presents a clinical discussion of a 42-year-old pregnant woman who experienced vaginal hemorrhage. The article follows the NEJM's Case Records format, which typically presents a challenging diagnostic case, discusses the differential diagnosis, and reveals the final diagnosis with teaching points for clinicians. The case focuses on the evaluation and management of obstetric hemorrhage in a patient of advanced maternal age.


Vaginal hemorrhage during pregnancy represents a potentially life-threatening emergency requiring rapid diagnosis and intervention. Case reports like this provide educational value for clinicians by illustrating diagnostic reasoning, management strategies, and potential complications in high-risk obstetric scenarios, particularly in women of advanced maternal age who face increased pregnancy-related risks.


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New England Journal of Medicine, Volume 395, Issue 17, Page 1745-1754, October 29, 2026.

Source: Case 31-2026: A 42-Year-Old Pregnant Woman with Vaginal Hemorrhage