AI Insight
Chronic kidney disease (CKD) causes approximately one death every 20 seconds and is projected to become the fifth leading cause of death globally by 2040. While type 2 diabetes is a significant contributor to CKD progression, over 50% of cases requiring kidney replacement therapy stem from other causes. In Europe, diabetes ranks only fourth among causes of kidney failure, behind glomerular diseases, inherited kidney diseases, and cases of unknown origin.
Why it matters
This highlights the critical need for CKD treatments that extend beyond diabetes-focused interventions, as the majority of kidney failure cases have non-diabetic origins. Addressing the full spectrum of CKD causes is essential for reducing the rapidly growing global burden of kidney disease and associated mortality.
Chronic kidney disease (CKD) causes one death every 20 seconds.1 CKD ranks among the fastest growing global causes of death, forecast to become the fifth most common cause of death by 2040. Type 2 diabetes is a common cause of CKD progressing to kidney failure. However, over 50% of incident kidney failure requiring kidney replacement therapy is due to other causes. Diabetes only ranks fourth among prevalent kidney replacement therapy causes in Europe, after glomerular diseases, inherited kidney diseases, and unknown cause.
Source: [Comment] Finerenone: kidney protection beyond type 2 diabetes