Castration-resistant prostate cancer

Castration-resistant prostate cancer is a type of prostate cancer that continues to grow and spread even when testosterone levels are lowered through hormone therapy, which normally helps slow the disease. This occurs because cancer cells develop clever ways to survive and thrive without relying on testosterone, either by adapting their internal machinery or by finding alternative sources of male hormones in the body. Understanding how these cancer cells become resistant is crucial for developing new treatments to help patients whose tumors no longer respond to standard hormone-blocking therapies.