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Mineralocorticoid receptor

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The mineralocorticoid receptor is a protein found in cells throughout your body that responds to hormones like aldosterone, which help regulate water and salt balance in your blood and tissues. When these hormones bind to the receptor, it triggers a cascade of cellular processes that control how much sodium your kidneys reabsorb and how much potassium they excrete, ultimately maintaining the proper fluid levels and blood pressure your body needs to function. Scientists study this receptor because problems with its function can lead to conditions like high blood pressure or electrolyte imbalances, and because drugs targeting it have become important treatments for heart disease and kidney disease.

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