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Smallpox

THINKS
Disease progression mechanism
Infection
Incubation
Fever
Rash
Resolution
LEARNS
Viral biology and transmission
Variola Virus
DNA virus hijacks human cells
Respiratory Spread
Droplets transmit between people
Pustule Formation
Fluid-filled skin lesions form
30% Mortality
High fatality rate untreated
Smallpox
Eradicated viral killer disease
SHAPES THE WORLD
Global health impact
Vaccination
First vaccine ever developed
Eradication
Only human disease eliminated
300M Deaths
Killed millions in 20th century
Bioweapon Concern
Potential security threat remains
Immunology
Advanced understanding of immunity
Public Health
Model for disease elimination
From data to real-world impact
Data
The foundation
Models
Built and trained
Decisions
Actionable insights
Impact
Creating real value

Smallpox is an ancient, devastating infectious disease caused by the variola virus, which produces characteristic fluid-filled pustules across the skin and kills approximately 30% of those infected. It spreads from person to person through respiratory droplets and contact with infected materials, making it one of hi…

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