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Keto Diet Slashes Liver Fat by Two-Thirds in Patients

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Fatty liver diseaseKetogenic dietMetabolic disorder

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A clinical trial comparing ketogenic, Mediterranean, and low-fat diets in people with obesity, prediabetes, and fatty liver disease found that all three diets resulted in approximately 10% body weight loss. However, the ketogenic diet demonstrated superior metabolic outcomes, reducing liver fat by 67% compared to 45% for the other two diets. Additionally, about half of participants following the keto diet no longer met criteria for prediabetes after four to five months.


These findings suggest that dietary composition, not just weight loss, may play a significant role in improving metabolic health markers, particularly liver fat reduction. The results could inform treatment strategies for non-alcoholic fatty liver disease and prediabetes management, conditions affecting millions of people worldwide.


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A ketogenic diet outperformed Mediterranean and low-fat diets in several measures of metabolic health during a clinical trial involving people with obesity, prediabetes, and fatty liver disease. All three groups lost about 10% of their body weight, but keto reduced liver fat by 67%, compared with 45% for the other diets. About half of the keto group also no longer qualified as having prediabetes after four to five months.

Source: Keto diet cut liver fat by 67% in a clinical trial