Physics

Migrating cells spontaneously form spiral patterns in continuous flow systems

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ChiralityPattern formationCollective cell mi…

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Researchers observed the spontaneous formation of chiral (handedness-preferring) multi-armed spiral patterns in migrating cell populations when cells were continuously supplied to an open system. These dynamic spiral structures emerged from collective cell migration behaviors rather than being predetermined by individual cell properties. The study demonstrates how simple physical and biological rules governing cell movement can lead to complex, organized patterns at the population level.


This finding helps explain how cells self-organize during critical biological processes like wound healing, embryonic development, and tissue formation. Understanding these emergent collective behaviors could inform strategies for tissue engineering and regenerative medicine applications.


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Source: Emergence of chiral multi-armed spirals in an open system of migrating cells under continuous cell supply