Medicine

Millions of seniors with dementia take medications that could worsen cognition

How the science connects

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AI Insight

Adults aged 65 and older with cognitive disorders such as dementia face increased risks when taking prescription medications for central nervous system conditions like anxiety, sleep problems, and psychosis. These drugs are associated with higher rates of emergency department visits, more frequent and prolonged hospitalizations, deteriorating mental health, and an elevated risk of premature death in this vulnerable population.


This finding highlights a significant medication safety concern for elderly patients with cognitive impairment, suggesting that prescribing practices may need revision to reduce harm. Healthcare providers should carefully evaluate the risk-benefit ratio when prescribing CNS medications to older adults with dementia and similar conditions.


Adults 65 and older with cognitive disorders such as dementia are more likely to suffer negative effects from drugs that treat central nervous system conditions, including anxiety, sleep problems and psychosis. This means more emergency department visits, more frequent and longer hospitalizations, poorer mental health and a greater risk of premature death.

Source: One-third of older adults with cognitive disorders are taking prescription drugs that could harm them