Biology

New platform speeds bacterial gene mapping for better biotech design

How the science connects

Genetic engineeringSynthetic biologyMicrobial metabolism

AI Insight

Researchers at Oak Ridge National Laboratory have developed a new platform that identifies genetic switches controlling microbial metabolism, enabling precise engineering of bacteria into biomanufacturing systems. The technology allows scientists to rapidly reprogram bacterial genes to optimize production of specific chemicals, materials, and enable extraction of critical minerals. This genetic mapping approach accelerates the conversion of microorganisms into customized biotechnology tools for industrial applications.


The platform could strengthen domestic manufacturing capabilities by enabling bacteria-based production of valuable compounds without relying on traditional chemical synthesis or foreign supply chains. It has potential applications in sustainable chemical manufacturing, biomaterial production, and recovery of rare earth elements and critical minerals needed for electronics and clean energy technologies.


Scientists at the Department of Energy’s Oak Ridge National Laboratory have created a platform that pinpoints genetic triggers that turn microbes into efficient factories for new chemicals and materials. The method enables rapid, precise reprogramming of bacteria as biotechnology tools, supporting domestic production of valuable products and recovery of critical minerals and materials to enhance the nation’s supply chains and global competitiveness.

Source: New platform speeds bacterial gene mapping for better biotech design