Medicine

Ovary identity shift after menopause may contribute to inflammation

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Research in mice suggests that ovaries do not become inactive after menopause but instead undergo an identity shift to become a different type of organ with a role in promoting inflammation. This challenges the previous assumption that post-menopausal ovaries are merely dormant tissues. The findings indicate that these transformed ovaries may actively contribute to inflammatory processes in the body.


This discovery could help explain why post-menopausal women experience increased rates of inflammatory conditions and age-related diseases. Understanding this organ transformation may lead to new therapeutic approaches for managing inflammation and associated health conditions in older women.


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We used to think post-menopausal ovaries sat inert in the body, but evidence from mice suggests they may instead turn into an organ with a role in inflammation

Source: Ovary identity shift after menopause may contribute to inflammation