Chemistry

Pomegranate peels enable greener detection of antipsychotic drug asenapine

How the science connects

Green chemistry

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Researchers developed an environmentally friendly electrode sensor by combining graphite paste with zinc oxide nanoparticles synthesized from pomegranate peel extract and multi-walled carbon nanotubes. This green-synthesized electrode was used to detect asenapine maleate, an antipsychotic medication, using voltammetric analysis. The pomegranate peel extract serves as a natural reducing agent for nanoparticle synthesis, making the process more sustainable than conventional chemical methods.


This green chemistry approach offers a cost-effective and environmentally sustainable method for pharmaceutical quality control and drug monitoring. The technique could be applied in clinical settings for therapeutic drug monitoring and in pharmaceutical industries for quality assurance, while reducing reliance on toxic chemical reagents in sensor fabrication.


Source: Graphite paste electrode integrated with pomegranate peel extract-derived ZnO nanoparticles and MWCNTs for green voltammetric analysis of asenapine maleate