Interdisciplinary

Preprints are just as reliable as peer-reviewed papers, analysis reveals

AI Insight

An analysis of 70,000 biomedical preprints found that their central conclusions rarely change when subsequently published in peer-reviewed journals. This large-scale study challenges the common perception that preprints are inherently unreliable compared to formally published research. The findings suggest that preprint findings generally hold up through the peer review process.


This research supports the reliability of preprints as a source of scientific information, which could accelerate knowledge dissemination in biomedicine. The findings are particularly relevant for time-sensitive situations where waiting for formal publication could delay important discoveries or public health responses.


Understand the Science

Peer review Concept coming soon Preprint Concept coming soon Scientific publishing Concept coming soon

Nature, Published online: 10 July 2026; doi:10.1038/d41586-026-02167-3

Central conclusions rarely change when biomedical preprints go on to be published in journals.

Source: Think preprints are unreliable? Analysis of 70,000 studies might change your mind