Medicine

Progesterone hormone directly influences women’s mood, brain scans show

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NeuroimagingMood disorder

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Researchers at the University of Barcelona have identified a neurological mechanism linking progesterone levels to mood regulation in women. The study found that higher progesterone levels during the menstrual cycle correspond to less distinct activity patterns in brain regions responsible for emotional control. This provides concrete neural evidence for the hormone's influence on mood, which was previously well-documented but less understood at the brain activity level.


This research could improve understanding of premenstrual mood changes and related conditions, potentially leading to better targeted treatments for hormone-related mood disorders. The findings may also inform approaches to managing emotional symptoms associated with menstrual cycle fluctuations.


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The influence of the hormone progesterone on mood is well known. Now, researchers from the University of Barcelona have shown how higher levels of progesterone during the menstrual cycle are linked to less distinct patterns of activity in areas of the brain involved in controlling emotions.

Source: Brain scans reveal new link between progesterone and women's mood