Biology

Scientists grew ancient human brain cells that tracked time’s passage

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AgingNeurodevelopment

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Scientists successfully grew human brain cell clusters in laboratory conditions for seven years, the longest period on record. These peppercorn-sized brain organoids displayed aging patterns similar to those observed in actual human brains, indicating they underwent biological changes that mirrored natural temporal progression. The research demonstrates that lab-grown neural tissue can recapitulate fundamental aging processes found in living organisms.


This achievement provides researchers with a new tool to study human brain development and aging over extended periods without relying solely on animal models or post-mortem tissue. The ability to observe how brain cells age in controlled laboratory settings could accelerate research into neurodegenerative diseases and developmental disorders.


Peppercorn-sized clumps of human brain cells grown in a lab for a record seven years aged similarly to those inside our heads, suggesting they “recorded the passage of time,” scientists said Wednesday.

Source: Oldest human brain cells grown in lab 'recorded passage of time'