AI Insight
A recent study indicates that vitamin D2 supplementation may suppress the body's endogenous levels of vitamin D3, the more biologically active and efficient form of the vitamin. Researchers observed that vitamin D3 not only raises overall vitamin D status more effectively than D2, but may also contribute distinct immunological functions, particularly in defending against viral and bacterial pathogens. These findings are leading scientists to question whether D3 should be the standard recommended form for supplementation over D2.
Why it matters
Vitamin D supplements are among the most widely consumed dietary supplements globally, and if D2 actively diminishes D3 levels, current supplementation guidelines may need to be revised to optimize both bone health and immune function outcomes.
A surprising study suggests vitamin D2 supplements may reduce the body’s levels of vitamin D3 — the more effective form of vitamin D. Researchers found D3 not only boosts vitamin D status more efficiently, but may also play a unique role in helping the immune system fight off viruses and bacteria. The discovery is prompting scientists to rethink whether D3 should become the preferred choice for supplementation.
Source: Scientists warn popular vitamin D supplement may have a “previously unknown” downside