Taking HRT in perimenopause may ward off cardiovascular disease

AI Insight

Research suggests that hormone replacement therapy (HRT) initiated during perimenopause may reduce the risk of cardiovascular disease, including heart attacks and stroke. The protective effect appears to be timing-dependent, with evidence indicating that starting HRT during the perimenopausal transition period may be more beneficial for cardiovascular health than beginning treatment later in life.

Why it matters

This finding could inform clinical guidelines for HRT prescription and help women make more informed decisions about managing menopausal symptoms. The timing-critical nature of cardiovascular benefits suggests a potential window of opportunity for preventive intervention during perimenopause.