Physics

This deep-sea enzyme survives heat that destroys most proteins

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ExtremophilesNitrogen fixation

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Researchers have discovered that a deep-sea microorganism produces an extraordinarily heat-resistant enzyme capable of converting atmospheric nitrogen into ammonia at temperatures that typically denature most proteins. The enzyme's unique structural properties and a newly identified reaction state suggest it may represent an ancient evolutionary mechanism for nitrogen fixation. This finding provides insights into how nitrogen-fixing processes work at the molecular level.


Understanding this heat-stable enzyme could lead to the development of more efficient and environmentally friendly methods for producing ammonia-based fertilizers, which currently require energy-intensive industrial processes. The discovery may also inform biotechnology applications that require robust enzymes capable of functioning under extreme conditions.


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A deep-sea microbe uses an exceptionally heat-resistant enzyme to turn atmospheric nitrogen into ammonia at temperatures that would destroy most proteins. Its unusual structure and a newly observed reaction state may reveal an ancient, shared mechanism behind nitrogen fixation and could eventually inspire cleaner biotechnology and fertilizer production.

Source: This deep-sea enzyme survives heat that destroys most proteins