Biology

Toward planetary microbial systems biology

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Microbial ecologySystems biologyOmics

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This article proposes a framework called "planetary microbial systems biology" that combines multiple omics technologies, artificial intelligence, and coordinated field-laboratory studies to investigate Earth's microbiomes as interconnected systems at a global scale. The approach aims to move beyond studying individual microbial communities in isolation by examining how microbiomes across different environments interact and influence each other across the planet. This represents a shift toward understanding microbial life as a planetary-scale system rather than as discrete, localized communities.


Understanding microbiomes at a planetary scale could transform how we address global challenges including climate change, food security, and human health, as microbial communities play critical roles in biogeochemical cycles, agriculture, and disease. This framework could enable better predictions of how environmental changes will affect microbial ecosystems and their functions that support life on Earth.


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Planetary microbial systems biology, encompassing multi-omics, AI, and field-to-lab interaction, is proposed as a framework to study Earth’s interconnected microbiomes at a planetary scale.

Source: Toward planetary microbial systems biology