Chemistry

What a brewery can teach the chemical industry

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Enzyme engineeringFermentationBiomanufacturing

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Researchers are addressing a key challenge in bio-based manufacturing where toxic chemical products kill the microbes producing them. The team from the Sustainable Commodity Chemicals through Enzyme Engineering and Design project is applying principles from brewing processes to overcome this limitation. This approach could enable biological production of chemicals that are currently derived from petroleum.


This research could help transition chemical manufacturing away from oil-based processes toward more sustainable biological production methods. Solving the toxicity problem would expand the range of chemicals that can be produced using engineered microorganisms, potentially reducing the environmental impact of chemical manufacturing.


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What do you do when the chemical you want to make is toxic to the microbe making it? It is a problem that limits efforts to replace oil-based manufacturing with biology, and one that researchers in the Sustainable Commodity Chemicals through Enzyme Engineering and Design project are approaching by borrowing a principle from brewing.

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