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AI Now Assists in 90% of Biomedical Research Papers

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Artificial intelli…Biomedical research

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A study published in Nature found that approximately 90% of biomedical research papers published in December 2025 and archived in PubMed show evidence of assistance from artificial intelligence tools. This percentage represents a significant increase compared to earlier estimates of Large Language Model usage in scientific writing. The analysis focused specifically on papers indexed in PubMed, the primary database for biomedical and life sciences literature.


This finding reveals the rapidly accelerating integration of AI tools into scientific research workflows and academic writing. The widespread adoption raises important questions about research integrity, proper attribution of AI assistance, transparency in scientific publishing, and the need for updated guidelines on disclosure of AI use in scholarly work.


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Nature, Published online: 20 August 2026; doi:10.1038/d41586-026-02551-z

The figure, which is much higher than previous estimates of Large Language Model use, is for papers published in December and archived in PubMed

Source: Staggering 90% of biomedical papers now show signs of AI help