A never-before-seen picture of eagle migrations
In 1899, scientists began tracking avian migration by placing a small ring with an identifier around birds’ ankles. Researchers then had to recapture the birds elsewhere, leaving the journey between…
Biology
Rethinking bluegreen aphid control as insecticide resistance spreads
When an insecticide application fails to control bluegreen aphid, application conditions may not be the only cause. Research has identified resistant populations across southern Australia, confirming…
Indonesian rice genomes reveal genetic secrets behind key crop traits
Indonesian rice cultivars represent valuable genetic resources, yet many remain poorly characterized at the genomic level. Here, we generated 95.40 Gb of PacBio HiFi sequence data from seven…
The QxxR Motif of RNA Helicase Me31B Is Essential for Drosophila Female Fertility and Germline Development
The QxxR motif is evolutionarily conserved within DEAD-box RNA helicases, including Drosophila Me31B and human DDX6, which post-transcriptionally regulate gene expression during animal development. A…
Normal human cells carry surprisingly diverse patterns of genetic mutations
Over the course of a lifetime, somatic mutations accrue in normal human cells, causing variation in cell phenotype and engendering somatic evolution with outcomes ranging from the adaptive immune…
Scientists reveal how cancer drug inhibitors bind to key enzyme target
Accurate determination of kinase inhibitor binding modes could provide essential information for understanding resistance mechanisms and accelerating drug discovery. While conventional structural…
Influenza A virus H5N1 genotypes B3.13 and D1.1 show temperature-dependent restriction of replication in primary human respiratory epithelial cell cultures derived from the upper and lower respiratory tract.
H5N1 clade 2.3.4.4b avian influenza A viruses pose a significant threat to wild animal populations, domesticated animals, and potentially, the human population. For H5N1s to infect and transmit among…
Corpusome, a cross-body-site human microbiome corpus for representation learning
Machine-learning models of the human microbiome are trained mostly on stool samples from single cohorts, limiting cross-body-site representation and cross-study generalization. Progress is…
Anti-inflammatory Protein Reduces Brain Damage After Subarachnoid Hemorrhage
BACKGROUND: Subarachnoid hemorrhage (SAH) induces inflammatory responses and subsequent immune cell activation, which may contribute in cerebral vasospasm, microcirculatory impairment and poor…
Scientists Reveal Hidden Diversity in Newly Classified Bacterial Ribonuclease Family
Microorganisms across all domains of life engage in molecular conflict, deploying toxins to inhibit competitors or respond to biological threats. Among these, ribonuclease toxins are particularly…