Despite their therapeutic potential across a wide range of central nervous system (CNS) disorders, nucleic acid-based therapeutics are limited by inefficient delivery to deep brain regions at…
Small nucleolar RNAs (snoRNAs) are a class of non-coding RNAs that play critical roles in guiding 2′-O-methylation (Nm) and pseudouridylation modifications of RNAs. In Drosophila melanogaster,…
Aim Human land-use change contributes to biodiversity declines, but also creates new niches that facilitate novel biotic interactions. These interactions can reshape ecological communities and…
Somatic mutations accumulate throughout life and have been hypothesized to drive organismal decline. Yet whether these mutations are distributed randomly or whether cells shield their most critical…
Long before his days of research, Christian Couch was just a kid marveling at the butterflies in the Florida Museum of Natural History’s Butterfly Rainforest. Years later, after enrolling as an…
Northwestern Medicine scientists have developed a new experimental method to analyze conformational fluctuations in protein domains on a uniquely large scale, which may improve data-driven modeling,…
Scientists have reported it for decades: overpopulation can impair reproduction. Crowded chickens lay fewer eggs. Crowded mice have smaller broods. In humans, several studies have associated…
Researchers at the University of Guelph have developed a faster way to identify potential drug targets against a dangerous fungal pathogen, allowing for the study of hundreds or thousands of genes…
The element sodium plays a key role in nervous system function. An international research team headed by the Institute of Neurobiology at Heinrich Heine University Düsseldorf (HHU) has now conducted…
Scientists have identified dozens of previously overlooked cultural behaviors in wild chimpanzees, suggesting that the great ape’s culture extends far beyond complex skills like tool use. In a single…