Spatial organization and temporal regulation of membrane components are essential for achieving complex functions in artificial cells, such as cell division and signalling. DNA-based molecular tools…
Small molecules that target structured RNA hold therapeutic promise across a wide range of diseases, yet the structural principles governing RNA-ligand recognition remain poorly defined. Here we…
Reliable and scalable soft implantable neural interface fabrication remains a key challenge for chronic bioelectronic applications. Here, we present a transparent soft microelectrode fabricated with…
Autoinhibition is a fundamental regulatory mechanism for kinesins, including the heterotrimeric kinesin-2 complex (KIF3A/KIF3B/KAP3), which mediates cytoplasmic cargo transport and anterograde…
Appropriate activation of innate immune receptors is vital for the plant immune system. Immune activation must be strong and robust upon invasion by rapidly evolving pathogen species, while staying…
Paper-based diagnostics such as lateral flow assays (LFAs) and microfluidic paper-based analytical devices (PADs) have attracted considerable attention because of their low cost, portability, and…
Co-culturing cells with mismatched densities, where one cell type adheres to surfaces while the other floats, represents a fundamental challenge in cell biology. This is particularly evident in…
Leukocyte immunoglobulin-like receptor B4 (LILRB4, ILT3) is an inhibitory immune checkpoint expressed on myeloid cells, where it contributes to immunosuppression within the tumor microenvironment….
Severe droughts, intense floods, and heat waves are pushing river ecosystems beyond their natural limits of resilience. A review of data on river systems across several continents published in the…
Fish who display dominant traits are more at risk of consuming microplastic pollution than others in their social group, according to new research. The study, led by the University of Glasgow and…