by Titas Sil, Caitlin H. Kowalski, Sierra Scamfer, Natalie Copeland, Matthew F. Barber
Antimicrobial peptides (AMPs) constitute key components of innate immunity across the tree of life. Canonical…
by Santosh Kumar Srivastava, Guo Wei Foo, Haosheng Shen, Yuanzhi He, Kwok Soon Wun, In Young Hwang, Michael S. Goodson, Nikhil Aggarwal, Matthew Wook Chang
Host stress is associated with elevated…
What Is Mitochondrial Dysfunction and Cellular Adaptation — And Why Does It Matter? When your cells face stress—whether from toxins, oxygen deprivation, or injury—they don’t simply surrender. Instead, they activate an intricate emergency response system, negotiating with their own internal power plants to survive under adverse conditions. Yet sometimes this negotiation fails, and mitochondria begin … Read more
arXiv:2608.22627v1 Announce Type: cross
Abstract: Stochastic reaction networks are continuous-time Markov chain models for interacting populations, with applications in biochemistry, epidemiology,…
arXiv:2608.22849v1 Announce Type: cross
Abstract: Full-length RNAs, particularly messenger RNAs, often exceed the context lengths used to pretrain existing RNA foundation models, limiting…
arXiv:2608.15382v2 Announce Type: replace-cross
Abstract: Large language models (LLMs) are increasingly proposed for healthcare decision support, but their evaluations still reward single-answer…
Operant paradigms are powerful tools to quantify motivation and reward. Traditionally, operant conditioning research has been limited to food and drug reinforcers. Recent advances in commercially…
Chondrosarcoma is a hyper-vascularised, chemoresistant cartilage malignancy driven by VEGF-centred angiogenesis, and local adipose depots are increasingly recognised as paracrine drivers of tumour…
Replication is central to most experimental and sampling designs, increasing inferential power and capturing fine-scale data heterogeneity. However, its importance remains poorly evaluated in some…
Structure and disorder predictors are increasingly used as decision-grade tools in protein engineering and in the analysis of newly emerged proteins, yet how the current state-of-the-art behaves on…