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Atom-level Protein Representation Learning Improves Protein Structure Prediction

22. May 2026 by a3-admin

arXiv:2605.22133v1 Announce Type: new
Abstract: Recent advances in generative modeling show that pretrained representations can improve generation as conditioning features or alignment targets….

Categories Biology

Drivers of Transient Dynamics and Persistence in Dengue: Insights from Sensitivity and Stochastic Modeling

22. May 2026 by a3-admin

arXiv:2605.21787v1 Announce Type: new
Abstract: We investigate how key epidemiological parameters shape both seasonal epidemics and the persistence of dengue transmission. Our findings confirm known…

Categories Biology

Mitochondrial activity directs nutrient uptake and patterning in human gastrula models.

22. May 2026 by a3-admin

There is increasing awareness that nutrient uptake and utilization play key roles in determining cell fate specification during development. Mitochondria integrate these nutrient inputs translating…

Categories Biology

Structures of Cas9-Bound Double-Stranded DNA Mini-Circle Reveal Impacts of DNA Shape on Cas9 Target Interrogation

22. May 2026 by a3-admin

CRISPR-Cas9 is an RNA-guided endonuclease that cleaves double-stranded DNA at specific sites and has been adapted as a powerful tool for genome manipulation. Cas9 recognizes its target through…

Categories Biology

Comprehensive Complete-Genome Analysis of Lactobacillaceae and Bifidobacteriaceae Reveals Strain-Specific Metabolic Interactions in Chinese Gut Microbiota

22. May 2026 by a3-admin

Bifidobacteriaceae and Lactobacillaceae are key probiotic families and widely used in food production, yet a comprehensive understanding of strain functions and their gut microbial interactions based…

Categories Biology

CO2 fixation mediated by the carbon concentrating mechanism enables a rapid response to nitrogen deprivation in cyanobacteria

22. May 2026 by a3-admin

Cyanobacteria are leading biomass producers of the ocean whose ecological success relies on their ability to respond to dynamic availability of nutrients like CO2 and nitrogen, which require distinct…

Categories Biology

Molecular and spatial characterization of baicalin from Scutellaria baicalensis hairy root culture

22. May 2026 by a3-admin

This study presents the structural verification of baicalin isolated from a hydroethanolic extract of an in vitro Scutellaria baicalensis root culture using Xray diffraction analysis and a set of NMR…

Categories Biology

MRI-based dental maturity in newborns reflects prenatal exposures and predicts timing of primary tooth eruption

22. May 2026 by a3-admin

Primary tooth development is shaped by prenatal experience and has consequences for childhood caries and lifelong oral health. However, evidence linking prenatal conditions to dental development has…

Categories Biology

Cognitive engagement induces area-specific fingerprints of dopamine, acetylcholine, serotonin, glutamate and GABA in prefrontal cortex and striatum

22. May 2026 by a3-admin

Cholinergic, dopaminergic and serotonergic neuromodulation has pervasive effects on circuit functions in prefrontal cortex (PFC) and striatum and interact with glutamatergic and GABAergic…

Categories Biology

Min-frame transformation enables more sensitive viral genome alignment

22. May 2026 by a3-admin

Motivation: Maximal unique matches (MUMs) are a fundamental primitive in genome comparison, where they serve as high-confidence anchors for downstream multiple genome alignment. However, because MUMs…

Categories Biology
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