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Dozens of scientific studies compromised by misidentified antibodies

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Antibody

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A researcher has identified dozens of scientific studies that used incorrect antibodies in their experiments. This represents another instance of a commonly-used laboratory tool being misapplied in research, potentially affecting the validity of the findings in those studies. The discovery highlights ongoing quality control issues in antibody validation and usage across scientific research.


Antibodies are fundamental tools in biomedical research, used to detect and measure specific proteins in experiments. When wrong antibodies are used, research conclusions may be invalid, potentially affecting subsequent studies that built upon those findings and wasting research resources.


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Nature, Published online: 21 August 2026; doi:10.1038/d41586-026-02352-4

The case is the latest example of a scientific workhorse being misused in experiments.

Source: Sleuth identifies dozens of studies that used the wrong antibody