Medicine

Fish oil supplements don’t improve brain health, two-year study reveals

How the science connects

Alzheimer's diseaseClinical trialOmega-3 fatty acid

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A two-year clinical trial investigated whether fish oil supplements could improve brain health and memory or prevent Alzheimer's-related brain deterioration. While the supplements successfully increased omega-3 fatty acid levels in the brain, they produced no measurable improvements in memory function or protection against brain shrinkage associated with Alzheimer's disease. The findings suggest that omega-3 benefits may depend on obtaining these nutrients through whole foods rather than isolated supplements.


This challenges the widespread practice of taking fish oil supplements specifically for brain health and cognitive protection. The results indicate that consumers spending money on these supplements for dementia prevention may not be receiving the expected benefits, and that dietary sources of omega-3s may be more effective than supplementation.


A surprising two-year clinical trial found that fish oil supplements successfully delivered omega-3s to the brain but failed to improve memory or protect against Alzheimer’s-related brain shrinkage. Researchers suspect that getting these nutrients through a healthy diet may offer benefits that supplements alone cannot provide.

Source: Millions take fish oil for brain health. A two-year study found no benefit