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This Nature commentary argues that neuroscience has become overly reliant on computational metaphors that treat the brain as if it were a computer processing information. The author contends this framework limits understanding of neural function and calls for alternative theoretical approaches that better capture the brain's biological nature. The piece advocates for moving beyond information processing models to develop new frameworks for understanding brain function.
Why it matters
The computational metaphor has dominated neuroscience research for decades, influencing experimental design, interpretation of results, and funding priorities. Shifting theoretical frameworks could redirect research efforts and potentially lead to breakthroughs in understanding consciousness, mental illness, and brain disorders that current models have struggled to explain.
Nature, Published online: 25 May 2026; doi:10.1038/d41586-026-01619-0
Neuroscience needs to stop treating the brain as if it is a computer.