Chemistry

New fluorescent dye detects pH levels across acidic and alkaline conditions

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Researchers developed a new red fluorescent compound based on bis-allyl rhodanine chemistry that functions as an optical pH sensor across a wide range of acidic to alkaline conditions. The fluorophore exhibits reversible OFF/ON fluorescence switching behavior, turning off in acidic conditions and on in alkaline conditions, while maintaining durability through multiple cycles. This rhodanine-based sensor demonstrates robust performance characteristics suitable for continuous pH monitoring applications.


This advancement provides a more durable and reversible optical method for pH measurement across broad ranges, which could improve monitoring in industrial processes, environmental analysis, and biological systems where traditional pH sensors may degrade or fail. The red fluorescence wavelength is particularly advantageous for biological applications due to reduced interference and better tissue penetration.


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Source: An innovative bis-allyl rhodanine robust red fluorophore for wide-range optical pH sensing with reversible and durable acidic–alkaline OFF/ON fluorescence