Chemistry

PFAS in most medicines can be replaced with alternatives

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A study by the University of Freiburg, commissioned by the German Environment Agency and published in Sustainable Chemistry and Pharmacy, has found that many pharmaceutical active ingredients containing per- and polyfluorinated alkyl compounds (PFAS) can be replaced with alternative substances. PFAS are persistent environmental pollutants that cause long-lasting ecological harm. The research provides a basis for physicians to preferentially prescribe PFAS-free medications when therapeutically appropriate.


This finding could significantly reduce environmental contamination from pharmaceutical PFAS while maintaining treatment efficacy. It provides actionable information for healthcare providers to make more environmentally sustainable prescribing decisions without compromising patient care.


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Certain medicines contain per- and polyfluorinated alkyl compounds, known as PFAS, which are causing increasing environmental harm because of their long-lasting effects. A study published in Sustainable Chemistry and Pharmacy by the University of Freiburg, commissioned by the German Environment Agency, shows that many PFAS-based active ingredients used in medicines can be replaced by alternative active ingredients. Based on the report’s findings, doctors will in the future be able to give preference to prescribing PFAS-free medicines, where this is appropriate from a therapeutic point of view.

Source: PFAS in most medicines can be replaced with alternatives