Medicine

Plague DNA Shows Why the Black Death Haunted Europe for Centuries

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Ancient DNA analysis has revealed that plague continued to return to Europe for over 400 years following the Black Death pandemic, with the pathogen evolving into new genetic lineages during this period. Researchers developed an improved dating method for ancient plague genomes that allows them to connect specific genetic samples to documented historical outbreaks. The study shows that plague spread across Europe through multiple routes including trade networks, human migration patterns, and military conflicts.


This research provides crucial insights into how infectious diseases persist and evolve over centuries, which can inform modern epidemic preparedness and response strategies. The improved dating methodology developed in this study could be applied to other ancient pathogens, enhancing our understanding of historical disease patterns and their relationship to human activity.


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Ancient DNA reveals that plague repeatedly returned to Europe for more than 400 years after the Black Death, evolving into new lineages and spreading through trade, migration, and war. Researchers also developed a method to date ancient plague genomes more precisely, linking many of them to specific outbreaks recorded in historical sources.

Source: Ancient DNA reveals how plague kept returning for 400 years after the Black Death