Biology

Scientists crack 50-year mystery of wheat’s resistance to destructive fly

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Researchers at the University of Maryland have successfully cloned a wheat gene that confers resistance to Hessian fly larvae, ending a 50-year search for this genetic mechanism. The team demonstrated that the gene product directly interacts with a protein produced by the insect pest. This breakthrough provides new insights into the molecular basis of pest resistance in wheat crops.


This discovery could enable scientists to engineer improved pest resistance in wheat varieties, potentially reducing crop losses and decreasing reliance on chemical pesticides. Understanding the direct gene-protein interaction mechanism may also inform resistance strategies against other agricultural pests.


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Researchers at the University of Maryland and their collaborators have cloned a gene that makes wheat resistant to feeding by Hessian fly larvae and demonstrated its direct interaction with a protein produced by the insect. The research breaks through a longstanding barrier to understanding and engineering pest resistance in wheat. It is described in a research paper published Aug. 14, 2026, in the journal Science Advances.

Source: Wheat gene behind Hessian fly resistance cloned after 50-year search