Biology

Scientists insert large genes into crops without cutting DNA strands

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Researchers at KAUST have developed a novel genome editing technique that enables the insertion of large genetic sequences into rice and tobacco plants without creating DNA breaks. This method overcomes a longstanding limitation in plant biotechnology that has restricted the ability to introduce complex genetic information into plant genomes. The technique was successfully demonstrated in two economically important plant species.


This advancement could accelerate the development of crops with enhanced traits such as improved resilience to environmental stress and increased agricultural sustainability. The technology may also expand the use of plants as production systems for therapeutic compounds and biological molecules, offering a scalable alternative to traditional manufacturing methods.


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Researchers at King Abdullah University of Science and Technology (KAUST) have developed a new way to add large pieces of genetic information to plants, overcoming a challenge that has limited plant biotechnology for decades. The advance could help scientists build more complex traits into plants in the future, supporting research into areas such as crop resilience, sustainable agriculture, biotechnology and the use of plants as scalable platforms for producing therapeutics and biologics.

Source: Genome tool places large genetic sequences precisely in rice and tobacco without DNA breaks