Medicine

Severe asthma links to three recurring illness clusters across 2,700 patients in 11 countries

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ObesityAsthmaOsteoporosis

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A large-scale international study analyzing data from approximately 2,700 patients across 11 countries found that severe asthma is frequently accompanied by multiple comorbid conditions, including obesity and osteoporosis. These additional health conditions do not appear randomly but instead tend to group into three distinct recurring illness clusters among patients with severe asthma. The identification of these clusters suggests that severe asthma may manifest through several biologically or clinically distinct subtypes defined in part by their associated conditions.


Recognizing these comorbidity clusters could allow clinicians to better tailor treatment strategies for patients with severe asthma rather than applying a one-size-fits-all approach. This may improve disease management outcomes and reduce the risk of undertreating conditions that currently go undetected.


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Most people living with severe asthma are also battling other health conditions that go under the radar, a major new study has found. Researchers analyzing data from thousands of patients discovered that the additional illnesses—which range from obesity to osteoporosis—tend to appear in clusters.

Source: Severe asthma links to three recurring illness clusters across 2,700 patients in 11 countries