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Why Clinical Trials Get Terminated: Analysis Reveals Patterns in Failed Studies

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This is a correction notice for a previously published research article that examined methods for systematically evaluating clinical trials that were terminated early and registered in ClinicalTrials.gov. The original study analyzed a cohort of clinical trials from Germany and California to develop scalable approaches for assessing why trials were discontinued. The correction addresses errors or omissions in the original publication.


Understanding why clinical trials terminate prematurely is important for improving trial design, protecting research participants, and ensuring efficient use of research resources. Scalable assessment methods could help regulatory bodies and research institutions better monitor and learn from discontinued trials.


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by Samruddhi Suresh Yerunkar, Benjamin Gregory Carlisle, Delwen L. Franzen, Maia Salholz-Hillel, Daniel Strech, Susanne Gabriele Schorr

Source: Correction: Exploring scalable assessment methods for terminated trials in ClinicalTrials.gov: A cohort analysis of German and Californian trials