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Biology

Vision shapes neural maps of space through an ancient midbrain pathway

19. May 2026 by a3-admin

Mammals rely on their senses to establish their position in space. Neural activity in the hippocampus maps position, yet how sensory signals reach the hippocampus remains poorly understood. Here we…

Categories Biology

Primate Hippocampus Reveals Distinct Rules for Associative Synaptic Plasticity

19. May 2026 by a3-admin

Long-term potentiation (LTP) is a key cellular mechanism underlying learning and memory, but its conservation across species remains unclear. Using nonhuman primates (NHPs), we examined hippocampal…

Categories Biology

Robust lesion network mapping reveals genuine symptom-specific networks

19. May 2026 by a3-admin

Lesion network mapping (LNM) and its derivatives successfully integrate anatomically distributed brain loci into common symptom-associated functional networks, however, their statistical validity and…

Categories Biology

Anhedonia buffers the effects of early-life unpredictability on threat-reward decision-making.

19. May 2026 by a3-admin

Anhedonia-the diminished capacity to experience or anticipate pleasure-is among the most common consequences of early-life unpredictability, yet how these co-occurring conditions jointly shape…

Categories Biology

Iconic Sound-Shape Correspondences in Aphasia

19. May 2026 by a3-admin

Purpose: To examine speech iconicity for shape in aphasia, we compared iconicity ratings from people with aphasia to those from neurologically intact individuals and evaluated how iconicity relates…

Categories Biology

Error-driven representation learning in the mesolimbic system

19. May 2026 by a3-admin

In reinforcement learning, an agent learns to map representations of the environment state to predictions of future reward. Most prior work in neuroscience has assumed a fixed representation and…

Categories Biology

Reduced MOV10 reveals novel functional cortical connections in an increased fear response

19. May 2026 by a3-admin

The RNA helicase MOV10 is highly expressed in developing brain, is present in synapses and is required for embryonic viability. A murine brain-specific knockout of MOV10 (Mov10 Deletion) has a…

Categories Biology

Reduced cortical VPS26B levels are associated with altered glutamate receptor expression and synaptic protein loss in the primary motor cortex of a Parkinsonian mouse model

19. May 2026 by a3-admin

Parkinsons disease (PD) is associated with motor impairment and cortical synaptic dysfunction, which involve altered glutamate receptor trafficking, yet the underlying mechanisms remain incompletely…

Categories Biology

ToxCastLite: A portable semantic evidence graph linking in vitro bioactivity, in vivo toxicity, and exposure-use context

19. May 2026 by a3-admin

Motivation: The ToxCast database is a valuable resource for computational toxicology and new approach methodologies (NAMs), but the approximately 100GB MySQL distribution is difficult to use for…

Categories Biology

Emotional valence of conspecific vocalizations modulates auditory and limbic brain activity in juvenile pigs

19. May 2026 by a3-admin

Pig vocalizations convey information about the emotional states of individuals, varying with arousal and valence. Studies show that different call types reflect distinct emotional contexts and social…

Categories Biology
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