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Demonstrating real advantage of machine learning–enhanced Monte Carlo for combinatorial optimization

8. May 2026 by a3-admin

Proceedings of the National Academy of Sciences, Volume 123, Issue 19, May 2026. <br/>SignificanceIn this work, we address a question that has attracted intense interest in recent years:…

Categories Interdisciplinary

Sterol divergence across eukaryotic kingdoms determines membrane susceptibility to saponins, a class of plant defense compounds

8. May 2026 by a3-admin

Proceedings of the National Academy of Sciences, Volume 123, Issue 19, May 2026. <br/>SignificanceThe basis for the selective activity of saponins across organisms, and for plant…

Categories Interdisciplinary

Inflammasome adaptor protein ASC is a mechanistic checkpoint in IL-1β maturation

8. May 2026 by a3-admin

Proceedings of the National Academy of Sciences, Volume 123, Issue 19, May 2026. <br/>SignificanceInflammasomes are supramolecular complexes that activate caspase-1 and other inflammatory…

Categories Interdisciplinary

Reconstructing ancient genomes from gene counts: A robust likelihood framework with sampling bias correction

8. May 2026 by a3-admin

Proceedings of the National Academy of Sciences, Volume 123, Issue 19, May 2026. <br/>SignificanceHow has evolution shaped the diverse gene repertoires of extant genomes? We find that current…

Categories Interdisciplinary

MiR-155-driven loss of ICOSL and SOCS1 in EBV+ gastric cancers renders abundant cytotoxic T cells ineffective, enabling immune evasion

8. May 2026 by a3-admin

Proceedings of the National Academy of Sciences, Volume 123, Issue 19, May 2026. <br/>SignificanceCytotoxic T cells [cytotoxic T lymphocytes (CTLs)] play a critical role in antitumor immunity;…

Categories Interdisciplinary

Clinician behavior when skin tone affects test results

8. May 2026 by a3-admin

Proceedings of the National Academy of Sciences, Volume 123, Issue 19, May 2026. <br/>SignificanceThere is growing attention and concern about racial biases in some of the decision tools that…

Categories Interdisciplinary

D614G reshapes allosteric networks and opening mechanisms of SARS-CoV-2 spikes

8. May 2026 by a3-admin

Proceedings of the National Academy of Sciences, Volume 123, Issue 19, May 2026. <br/>SignificanceOur work reveals how the D614G mutation in the severe acute respiratory syndrome coronavirus 2…

Categories Interdisciplinary

Evolution of species’ range and niche in changing environments

8. May 2026 by a3-admin

Proceedings of the National Academy of Sciences, Volume 123, Issue 19, May 2026. <br/>SignificanceIn a time of accelerating climate change, we need a predictive theory of species’ range…

Categories Interdisciplinary

David Attenborough Has Inspired Countless Scientists. To Mark His 100th Birthday, Here Are Ten Living Things They’ve Named After Him

7. May 2026 by a3-admin

Researchers around the planet grew up watching documentaries hosted by the English broadcaster and naturalist, which sparked their love of the natural world. Now, their discoveries become tributes to…

Categories Interdisciplinary

What Causes Lightning? The Answer Keeps Getting More Interesting.

6. May 2026 by a3-admin

Armed with a slew of new instruments, physicists are closing in on one of nature’s oldest mysteries — and finding that storm clouds are seething with violent and unexpected phenomena. …

Categories Interdisciplinary
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