Biology

How the brain transforms what you want into action

AI Insight

A new study published in PLOS Biology reveals that the brain encodes not just the value of expected rewards, but also their specific identity. The research demonstrates that the lateral orbitofrontal cortex processes identity-specific reward expectations and communicates with the nucleus accumbens to guide goal-directed behavior and action selection. This challenges the traditional neuroeconomics view that focused primarily on reward value while overlooking what specific reward is being anticipated.


Understanding how the brain distinguishes between different types of rewards and translates specific expectations into motivated actions could inform treatments for disorders involving impaired decision-making and motivation, such as addiction or depression. This circuit-level insight may also help explain why individuals make different choices even when rewards have equal value.


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Reward system 4 articles Explore Concept → Orbitofrontal cortex Concept coming soon Neural encoding Concept coming soon

by Joey A. Charbonneau, Erin L. Rich

Neuroeconomics has long focused on reward values, ignoring their identity. A new PLOS Biology study shows that identity-specific reward expectations in the lateral orbitofrontal cortex steer goal-directed choices through a motivational circuit involving the nucleus accumbens.

Neuroeconomics has long focused on reward values, ignoring their identity. This Primer explores a new study in PLOS Biology that shows that identity-specific reward expectations in lateral orbitofrontal cortex steer goal-directed choices through a motivational circuit involving nucleus accumbens.

Source: Wanting this, not that: The neural circuit that turns specific expectations into actions