Correction: An international consensus on core reproducibility items in research
by The PLOS Biology Staff
Biology
A cell type-specific mechanism driving the rapid antidepressant effects of transcranial magnetic stimulation
A mouse model of repetitive transcranial magnetic stimulation reveals a prefrontal mechanism that links accelerated antidepressant behavioral effects to cell type-specific circuit plasticity.
Fronto-insular circuit mechanisms of accelerated intermittent theta burst stimulation
An optogenetic model of accelerated intermittent theta burst stimulation reveals cell type-specific plasticity mechanisms and a key role for a fronto-insular circuit in driving the antidepressant…
MIT BrainTrust supports neighbors living with brain injuries
Nearly 100 MIT students participate in a buddy program that assists Boston-area residents.
Cryptococcus neoformans adapts to host CO2 concentrations via metabolic and stress-response remodeling
by Laura C. Ristow, Emma E. Blackburn, Andrew J. Jezewski, Xiaorong Lin, Damian J. Krysan
Cryptococcus neoformans is an environmental pathogen that remodels its cellular physiology to survive within…
Biologist Joey Davis explores how cells build complex structures
His studies have shed light on the assembly instructions that govern ribosomes, the critical protein-building machines of the cell.
Disrupted molecular glue complex drives RAS inhibitor resistance
Cancers evade RAS-targeting molecular glues through distinct alterations that converge on disrupting synthetic complex formation, exposing strategies for improved drug design and rational combination…
How chromatin movement helps control gene expression
By monitoring these chromosomal structures over many timescales, MIT researchers found that chromatin helps bring genes closer to their regulatory elements.
Proteostasis sustains T cell differentiation potential and tumor-infiltrating lymphocyte function
Exhausted T cells experience a breakdown of proteostasis, characterized by unfolded protein accumulation and rescuable by E3 ubiquitin ligase activity. Targeting T cell proteostasis highlights a…
Six from MIT awarded 2026 Paul and Daisy Soros Fellowships for New Americans
Fellowship honors contributions of immigrants to American society by awarding $90,000 in funding for graduate studies.