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Biology

USP39 promotes antiviral defense through post-transcriptional control of RIG-I and stabilization of STING

11. May 2026 by a3-admin

by Jiazheng Quan, Xibao Zhao, Shaoying Chen, Hongrui Li, Wei Chen, Qianqian Di, Xunwei Li, Jiajing Zhao, Han Wu, Jin Chen, Yue Xiao, Zherui Wu, Weilin Chen

RIG-I and STING are critical for mediating…

Categories Biology

Structured water molecules drive activation and G protein selectivity in the GPR174 receptor

7. May 2026 by a3-admin

by Ying-Jun Dong, Kun Xi, Ya-Zhi Zhang, Jian-Heng Xue, Dan-Dan Shen, Shao-Kun Zang, Ruozhu Zhao, Hai Qi, Chunyou Mao, Wei-Wei Wang, Yan Zhang

G protein-coupled receptor 174 (GPR174), a key modulator…

Categories Biology

Targeted sequencing enhances detection of pangolin trafficking hotspots and dynamics of both domestic and global trade markets

7. May 2026 by a3-admin

by Sean P. Heighton, Jérôme Murienne, Mukesh Thakur, Alain Didier Missoup, Wirdateti Wirdateti, Chabi Sylvestre Djagoun, Sery Bi Gonedelé, Gabriel Ngua Ayecaba, Brice Roxan Momboua, Flobert…

Categories Biology

The KMT2F histone methyltransferase interacts with the RNA polymerase I machinery to promote ribosomal RNA transcription

7. May 2026 by a3-admin

by Kaisar Ahmad Lone, Amit Mahendra Karole, Geethanjali Ravindran, Shweta Tyagi

Trimethylation of histone 3 lysine 4 (H3K4me3) is a mark of active transcription, and its regulatory role in RNA…

Categories Biology

Environmental uncertainty shapes human effort learning

7. May 2026 by a3-admin

by Rong Bi, Jan Grohn, Patricia L. Lockwood, Miriam C. Klein-Flügge, Lilian Weber

Humans show remarkable flexibility in adapting their behaviour to constantly changing environments. This…

Categories Biology

Correction: An international consensus on core reproducibility items in research

7. May 2026 by a3-admin

by The PLOS Biology Staff

Categories Biology

A cell type-specific mechanism driving the rapid antidepressant effects of transcranial magnetic stimulation

7. May 2026 by a3-admin

A mouse model of repetitive transcranial magnetic stimulation reveals a prefrontal mechanism that links accelerated antidepressant behavioral effects to cell type-specific circuit plasticity.

Categories Biology

Fronto-insular circuit mechanisms of accelerated intermittent theta burst stimulation

7. May 2026 by a3-admin

An optogenetic model of accelerated intermittent theta burst stimulation reveals cell type-specific plasticity mechanisms and a key role for a fronto-insular circuit in driving the antidepressant…

Categories Biology

MIT BrainTrust supports neighbors living with brain injuries

6. May 2026 by a3-admin

Nearly 100 MIT students participate in a buddy program that assists Boston-area residents.

Categories Biology

Cryptococcus neoformans adapts to host CO2 concentrations via metabolic and stress-response remodeling

5. May 2026 by a3-admin

by Laura C. Ristow, Emma E. Blackburn, Andrew J. Jezewski, Xiaorong Lin, Damian J. Krysan

Cryptococcus neoformans is an environmental pathogen that remodels its cellular physiology to survive within…

Categories Biology
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