Eroding ACA enrollment portends higher insurance rates
Enrollment in the Affordable Care Act continues to erode as some customers struggle to make premium payments, with the declining numbers churning market uncertainty for insurers. In response,…
Medicine
Rollback of PFAS drinking water standards raises safety fears
The U.S. Environmental Protection Agency (EPA) said Monday it wants to roll back some regulations on “forever chemicals” in drinking water put into place in 2024.
Self-reported family history underestimates heart attacks among close relatives
A new study from Karolinska Institutet shows that people’s own reports of heart attacks in the family only partially correspond with register data. The findings suggest that heart attacks among…
Early birth safer for mother and baby in high blood pressure pregnancies, researchers find
Planned early birth for pregnant women with high blood pressure cuts maternal complications by nearly half and reduces the risk of stillbirth, without increasing the likelihood of cesarean section,…
Study finds substandard bowel cancer care for people with learning disability
People with a learning disability are at higher risk of developing bowel cancer, yet face significant barriers at nearly every stage of the care pathway, University of Manchester and Christie NHS…
Bacteriological contamination of drinking water from source to point of consumption in Ivorian households: a nationwide analysis of the 2021 Demographic and Health Survey
Background Bacteriological contamination of drinking water remains a major public health burden in sub-Saharan Africa, yet the full contamination chain from source to household has rarely been…
The economic gains of tissue papers hygiene benefits
Background: The choice of hand-drying method affects microbial contamination levels but its economic consequences have not been systematically quantified. Methods: By applying a quantitative…
A proteomic polygenic score to identify IL-18 driven inflammatory bowel disease
High levels of IL-18 have been causally implicated in IBD risk and may represent a unique mechanism driving IBD yet to be therapeutically targeted. To identify individuals predisposed to increased…
Methotrexate and Prednisolone compared to placebo and prednisolone in the treatment of Erythema Nodosum Leprosum – an international multicentre, double-blind randomised controlled clinical trial – MaPs in ENL
Background Erythema nodosum leprosum (ENL) is a severe inflammatory complication of leprosy that often requires prolonged corticosteroid therapy which is associated with adverse effects. Methotrexate…
Computational Transformation of Chemical Biology for Precision Therapeutics: Facilitating In-Silico Study of Role of Cuproptosis in Early Detection of Alzheimers Disease
Background: Alzheimers disease (AD) is a multifactorial neurodegenerative disorder in which copper dyshomeostasis, mitochondrial stress, oxidative injury and immune dysregulation may contribute to…