Medicine – Page 35 – Science Feed

Editorial Expression of Concern: Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer

5. December 2025 by Source Author

Addendum to: Nature Medicine https://doi.org/10.1038/nm.2090, published online 24 January 2010. The Editors would like to alert readers that a concern has been raised regarding the similarity of Fig. 2d Cisplat+ pr-cas3 blots representing MDA231 and BT549 cells. These blots appear to share some highly similar features; however, due to the age of the article and … Read more

In vivo CRISPR screen reveals regulation of macrophage states in neuroinflammation

4. December 2025 by Source Author

Nature Neuroscience, Published online: 04 December 2025; doi:10.1038/s41593-025-02151-6 De la Rosa et al. developed an in vivo CRISPR screening system to dissect macrophage regulation in multiple sclerosis models, revealing key cytokine signaling pathways that control myeloid cell behavior in neuroinflammation.